Scientist II/III, Antibody Kinetics Biotherapeutics

Description

Boehringer Ingelheim is currently seeking a talented and innovative Scientist II/III to join the Antibody Generation Group within the Biotherapeutics Department located at our US headquarters in Ridgefield, CT. This position will be responsible for designing, executing, and interpreting Surface Plasmon Resonance (SPR) experiments to characterize binding interactions and kinetics of biotherapeutic modalities, including antibodies and protein based therapeutics. This role applies advanced kinetic data analysis to inform lead selection, affinity maturation, and developability assessments in biotherapeutic discovery programs. This individual will be expected to make major contributions to the generation of best-in-class and first-in-class therapeutics to address major unmet medical needs. 

Contributes to R&D discovery research by performing scientific research. Implements protocols as required. Provides expertise within a technical specialty required for skill center productivity.  

As an employee of Boehringer Ingelheim, you will actively contribute to the discovery, development and delivery of our products to our patients and customers. Our global presence provides opportunities for all employees to collaborate internationally, offering visibility and opportunity to directly contribute to the companies' success. We realize that our strength and competitive advantage lie with our people. We support our employees in a number of ways to foster a healthy working environment, meaningful work, mobility, networking and work-life balance. Our competitive compensation and benefit programs reflect Boehringer Ingelheim's high regard for our employees. 

Duties & Responsibilities

• Independently design, execute, and interpret routine SPR experiments to characterize antibody-antigen interactions, generating high-quality kinetic data that supports antibody discovery and research objectives. 
• Apply established kinetic analysis approaches to evaluate binding interactions, analyze experimental data, draw scientific conclusions with input from supervisor and technical teams as appropriate, and effectively communicate results to project teams and at internal meetings. 
• Demonstrate a clear understanding of assigned assays and generated data, including their application within the antibody discovery process, ensuring accurate interpretation, documentation, and reporting of results. 
• Complete routine laboratory procedures independently and efficiently, requiring limited guidance on technical protocols and experimental execution. 
• Operate, troubleshoot, and maintain SPR instrumentation and associated laboratory equipment, ensuring instrument performance and data integrity. 
• Contribute to the evaluation and implementation of new SPR methodologies, technologies, and best practices to enhance assay performance, efficiency, and data quality. 
• Support laboratory excellence through process improvements, organization, and adherence to established workflows that promote operational effectiveness and reproducible results. 
• Collaborate with cross-functional discovery teams to provide data-driven insights that support project progression and decision-making. 
• Comply with applicable regulations, SOPs, and company policies, maintaining accurate scientific records and performing all work in a safe and compliant manner. 

Requirements

Scientist II Requirements: 

Bachelor’s degree from an accredited institution with three-plus (3+) years of experience in related scientific discipline or Master’s degree from an accredited institution in related scientific discipline or equivalent experience in related field  

Scientist III Requirements: 

Master’s degree in a related scientific discipline with 3+ years of industry experience or Bachelor’s degree with 6+ years or equivalent experience in molecular/cellular biology or 
biochemistry.  

Requirements for Both Levels: 

• Working knowledge of SPR-based technologies and the application of this technology in the drug discovery process to support project efforts, ranging from hit identification to mechanism- of-action studies is preferred 
• Knowledge of assay development methodologies for SPR specific instrumentation (BiacoreT200/S200, Biacore8K) supported by hands-on experience is preferred 
• Experience performing assay data capture and analysis using software such as, Biacore Insight, Spotfire, and Prism is beneficial 
• Ability to work independently as well as within a collaborative team environment with excellent writing, presenting and communication skills 
• Good record-keeping and organizational skills with exceptional attention to detail 
• Able to learn quickly and excel in a past-faced work environment; self-motivation, adaptability and positive attitude 

Eligibility Requirements:  

• Must be legally authorized to work in the United States without restriction.  
• Must be willing to submit to a background investigation, including verification of your past employment, criminal history, and educational background. 
• Must be willing to take a drug test and post-offer physical (if required). 
• Must be 18 years of age or older. 

Compensation Data

The base salary range for the Scientist II position is $75,000 to $122,000.   

The base salary range for the Scienitst III position is $90,0000 to $147,000.

The position may be eligible for a role specific discretionary bonus, relocation, and/or other compensation elements.  We continuously review market data and may adjust salary ranges as needed in the future.  Actual compensation will be based on job-related factors such as skills, experience, and qualifications, and other factors permitted by law. For an overview of our benefits please click here.