Post Doc - Electrophysiology & Sensor imaging of brain-obesity circuits

The Position

Join Us in Shaping the Future of Obesity Research

We are seeking a passionate and talented postdoctoral researcher who shares our ambition to uncover innovative therapeutic strategies for the treatment of obesity. We aim for in-depth investigation of critical neuronal and molecular mechanisms that could enhance and prolong the efficacy of anorexigenic therapeutics. Using cutting-edge technologies such as patch clamp and functional biosensor imaging in acute brain slices, you will explore how neuronal networks respond to pharmacological modulation.
As a neuroscience expert, you will contribute to interdisciplinary discussions and help expand our fundamental understanding of brain-mediated control of energy homeostasis.
Ready to make a difference? Apply now and be part of our journey toward transformative discoveries.

This position is part time eligible with min. 90%.

This Position is limited for 2 years.
Note: To make it easier to find our job advertisements, we use the usual designation "Post Doc". Of course, this advertisement is not only addressed to applicants directly after completing their doctorate, but to all qualified candidates

Tasks & responsibilities

• In your new role, you will investigate cellular and molecular changes in circumventricular brain areas during the development of obesity and in response to anti-obesity treatments.
• Furthermore, you will explore single-cell sequencing datasets for markers that predict sustained suppression of food intake through neuronal and network responses.
• You will establish and perform methods for AAV-mediated transduction of hypothalamic nuclei in mice, including labeling specific neuron populations and monitoring plastic network changes upon pharmacological treatments.
• In addition, you will set up and execute experiments to study neuronal properties in hunger/satiety circuits using electrophysiology techniques, such as cell-attached or whole-cell patch clamp and functional imaging in acute brain slices.
• You will present your findings at internal and external meetings and publish them in peer-reviewed journals.
• Moreover, you will collaborate in a stimulating environment with experts in the field and be part of interdisciplinary teams involving cellular and molecular biologists, chemistry experts, electrophysiologists and pharmacologists.

Requirements

• PhD in biology, neuroscience, or related fields in-depth knowledge in neuroscience
• Extensive hands-on experience in whole-cell patch clamp and electrophysiology recordings in acute brain slices; background in recording hypothalamic and/or brainstem neurons is advantageous
• Solid understanding of neurophysiology and experience in viral approaches to transduce rodent brain; stereotaxic surgery knowhow would be a plus
• Demonstrated track record of publications in scientific journals
• Ability to work in a drug-discovery oriented environment with multidisciplinary teams 
• Fluency in English (written and spoken); German language skills are desirable

Ready to contact us? 

If you have any questions about the job posting or process - please contact our HR Direct Team, Tel: +49 (0) 6132 77-3330 or via mail: hr.de@boehringer-ingelheim.com

Recruitment process:
Step 1: Online application - The job posting is presumably online until November 14th, 2025.
Step 2: Virtual meeting in the period from mid till end of November
Step 3: On-site interviews beginning of December

Please include the following documents when applying for this position: Cover letter and CV

Discover our Biberach site: xplorebiberach.com