Scientist - Peptide Analysis
About Human Pharmaceutical Business
With global presence, Boehringer Ingelheim has industry-leading expertise in medicine research and development. We are constantly developing the next generation of medical breakthroughs and successfully delivering innovations to meet the medical needs of the patients we serve in the following key areas of interest: cardiovascular, respiratory, metabolic diseases, immunology, oncology and central nervous system. In the future, we will accelerate the launch of more than 10 innovative medicines to meet the demand of Chinese patients.
Job Responsibilities
- Independently operate, maintain, troubleshoot, and optimize high-resolution mass spectrometry (HRMS) platforms, including Orbitrap-based systems.
- Develop, optimize, and troubleshoot analytical methods using LC-HRMS technologies.
- Conduct qualitative and quantitative analyses using LC-HRMS techniques for small molecules, impurities, degradation products and peptides.
- Generate, review, and maintain analytical data, reports, and technical documentation in compliance with laboratory quality requirements.
- Collaborate with cross-functional teams to provide analytical support for research, development, troubleshooting, and investigative projects.
- Provide technical expertise and scientific guidance on mass spectrometry applications and data interpretation and mentor junior analysts.
- Support laboratory compliance, safety programs, and continuous improvement initiatives.
Job Requirements
Education & Experience
- Master's degree in Analytical Chemistry, Chemistry, Pharmaceutical Sciences, Biochemistry, or a related scientific discipline.
- Minimum 3-5 years of hands-on experience in HRMS analysis.
- Proven experience operating and maintaining HRMS platforms, preferably Thermo Scientific Orbitrap systems.
- Experience supporting analytical investigations and solving complex analytical challenges.
Technical Competencies
- Strong knowledge of mass spectrometry principles, including ionization techniques, mass analyzers, and fragmentation mechanisms.
- Demonstrated expertise in HRMS data acquisition, spectral interpretation, and structural elucidation.
- Hands-on experience with sample preparation techniques for LC-HRMS applications.
- Proficiency with mass spectrometry software platforms such as Xcalibur or equivalent.
- Experience with LC-HRMS method development, optimization, and troubleshooting for peptides analysis
- Knowledge of GMP is considered an advantage.
Professional Skills
- Strong analytical thinking and problem-solving capabilities.
- Excellent data review, technical writing, and documentation skills.
- Effective communication and collaboration skills in cross-functional and multicultural environments.
- Strong commitment to laboratory quality, compliance, and scientific excellence.
- Good written skill in English is required.
- Good oral English is preferred.
- Communicate with candor - be willing to challenge and be challenged. Surface disagreements with respect. Present topics with conviction.
- Collaborate with a purpose - work together cooperatively, with a clear objective. Be efficient about when and how to involve others. Stay curious and open-minded.
- Decide and act with speed - make educated decisions faster. Drive action within and across teams.
- Innovate and drive change - create innovative solutions. Dare to drive change whilst constantly reflecting and learning.
- Deliver to win - take accountability to achieve competitive business outcomes, for the benefit of customers and patients.